Responses of juxtaglomerular cell suspensions to various stimuli.
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چکیده
منابع مشابه
Responses of juxtaglomerular cell suspensions to various stimuli.
Cell suspensions were prepared from rat renal cortical tissue by dispersion with 0.1% collagenase. Unit gravity sedimentation in a 1%-4% Ficoll gradient resulted in a single-cell suspension enriched in juxtaglomerular (JG) cells. Both the cellular renin activity and the amount of renin released into the supernatant increased with time when the suspensions were incubated for 1 hour at 37 degrees...
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Juxtaglomerular Cell Phenotypic Plasticity
Renin is the first and rate-limiting step of the renin-angiotensin system. The exclusive source of renin in the circulation are the juxtaglomerular cells of the kidney, which line the afferent arterioles at the entrance of the glomeruli. Normally, renin production by these cells suffices to maintain homeostasis. However, under chronic stimulation of renin release, for instance during a low-salt...
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ژورنال
عنوان ژورنال: Hypertension
سال: 1981
ISSN: 0194-911X,1524-4563
DOI: 10.1161/01.hyp.3.2.157